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2020年5月7日星期四

Six-month Observational Study: Effectiveness And Safety Of E-Cigarettes


In the past few years, consumer interest and the use of e-cigarettes (EC) as an alternative to smoking have increased exponentially. Many users of EC (also known as vapers) feel that using EC is safer than smoking CC(traditional cigarettes). In view of the effectiveness and safety of e-cigarettes for smoking cessation. The effectiveness and safety of single-user and dual-user e-cigarettes in Kuantan and Pekan Malaysia were observed with the aim of investigating nicotine cessation in EC and CC. The security problems of single EC and double (EC and CC) users within six months were also reported. From June 2015 to November 2015, they observed 218 unique EC patients and dual users over 6 months in Malaysia. Both groups underwent exhaled carbon monoxide and salivary cotinine analyses to validate nicotine cessation in EC and CC users. Adverse events and withdrawal symptoms were assessed on a self-report basis.

The data collection

At the beginning of the data collection, the only EC user is using EC only and the carbon monoxide (CO) level is less than or equal to 7ppm (PPM). However, for dual users using both EC and CC, CO value is greater than or equal to 8ppm. This indicates that the median CO level of dual users is significantly higher than that of single EC users. Apers are used in most vapers without tobacco. Therefore, the steam produced by them is free of carbon monoxide and tar. This indicates that the use of EC can reduce the toxicity of carbon monoxide more than the use of CC.


EC effect evaluation

Before the use of EC, the median intake of CC in both groups was 20 CC per day. After 6 months of follow-up, 148 dual users were included. The CC consumption rate for dual users did not decrease significantly between the start of data collection and week 24 (P < = 0.087). However, among the only EC users who resumed smoking, their daily CC consumption was still lower than that of double users (P <0.001). The only EC users showed a higher CC quit rate (29 to 15; OR: 6.33; And EC and CCS for combination (5 to 2; OR: 5.62; P ratio is used for double users <0.036), and there is a significant difference between the two.

Measurement of adverse reactions

Overall, dual users experienced more adverse effects throughout the study period than did single EC users. One case of COPD was recorded in the dual user group, and the only EC user did not report such a case during the entire study period. The main adverse reactions and withdrawal symptoms observed by dual users were cough, dyspnea and desire to smoke. Overall, the only EC users reported fewer side effects and withdrawal symptoms compared with dual users.

conclusion

Existing studies have shown that the risk level of ECs is lower than that of CCs. EC is currently available as an additional smoking cessation support tool in Malaysia, but appropriate procedures must be taken to encourage individual EC use and product quality. This has been recognized that electronic cigarettes have a certain effect on smoking cessation and effect, in order to the health of the body, confirmed that electronic cigarettes have quit smoking effect, how each country will treat electronic cigarettes? We'll see.

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Can E Cigarette Quit Smoking?A Six-Month Observational Study

In the past few years, consumer interest and the use of electronic cigarettes (EC) as an alternative to smoking have grown exponentially....